Journal: bioRxiv
Article Title: Medial preoptic area FoxO1 controls metabolic adaptation in a sexually dimorphic manner
doi: 10.1101/2025.06.25.661575
Figure Lengend Snippet: (A-I) Female control and FoxO1-KO MPOA mice were acclimated to Sable Promethion System for 2 days with chow diet access, followed by overnight fasting and subsequent refeeding with chow diet (n=5-6 per group). (A) Time course of energy expenditure. (B,C) Average energy expenditure during (B) fasting and (C) refeeding periods. (D-F) RQ measurements (D) over time with averages during (E) fasting and (F) refeeding. (G) Physical activity levels. (H,I) Food intake shown as (H) cumulative intake and (I) total intake during refeeding period. Data shown as mean ± SEM. (B, E, I) *P < 0.05, two-way ANOVA with Sidak’s post-hoc test.
Article Snippet: Indirect calorimetry measurements were conducted using the Promethion metabolic cage system (Sable Systems International, Las Vegas, NV, USA) at the Metabolic Phenotyping Core, Biologic Resources Laboratory, University of Illinois Chicago.
Techniques: Control, Activity Assay